Immunoreactive trypsinogen concentrations in infants with meconium ileus.

Protein in meconium from meconium ileus.

Meconium ileus is the earliest manifestation of cystic fibrosis, and several investigations have been undertaken to determine its cause. In 1952, Buchanan and Rapoport showed that the ash content of abnormal meconium was twice as high as that ofnormal newborns, and that whereas normal meconium consisted of only 7% protein, this rose to 85% in meconium ileus. We here show that the proteins conce...

Pediatric Meconium Ileus

Pediatric Meconium Ileus

Endothelin 1 concentrations in infants with meconium stained amniotic fluid.

Plasma endothelin 1 concentrations were determined in infants with meconium stained amniotic fluid. Plasma endothelin 1 concentration in the study group (5.23 pg/ml) was statistically higher than that in the control group (1.12 pg/ml). Cord blood pH and base excess values were significantly lower in infants with meconium stained amniotic fluid when compared with the control group. There was no ...

Pediatric Meconium Ileus